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Molecular Signaling Pathways Mediating Osteoclastogenesis Induced by Prostate Cancer Cells

BACKGROUND: Advanced prostate cancer commonly metastasizes to bone leading to osteoblastic and osteolytic lesions. Although an osteolytic component governed by activation of bone resorbing osteoclasts is prominent in prostate cancer metastasis, the molecular mechanisms of prostate cancer-induced ost...

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Detalhes bibliográficos
Main Authors: Rafiei, Shahrzad, Komarova, Svetlana V
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3881018/
https://ncbi.nlm.nih.gov/pubmed/24370273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-605
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