Anti-melanoma activity of T cells redirected with a TCR-like chimeric antigen receptor

Genetically modified T cells to recognize tumor-associated antigens by transgenic TCRs or chimeric antigen receptors (CAR) have been successfully applied in clinical trials. However, the disadvantages of either TCR mismatching or the requirement of a surface tumor antigen limit their wider applicati...

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Autors principals: Zhang, Ge, Wang, Lei, Cui, Honglian, Wang, Xiaomin, Zhang, Ganlin, Ma, Juan, Han, Huamin, He, Wen, Wang, Wei, Zhao, Yunfeng, Liu, Changzhen, Sun, Meiyi, Gao, Bin
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880964/
https://ncbi.nlm.nih.gov/pubmed/24389689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03571
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