HE4 (WFDC2) gene overexpression promotes ovarian tumor growth

Selective overexpression of Human epididymal secretory protein E4 (HE4) points to a role in ovarian cancer tumorigenesis but little is known about the role the HE4 gene or the gene product plays. Here we show that elevated HE4 serum levels correlate with chemoresistance and decreased survival rates...

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Main Authors: Moore, Richard G., Hill, Emily K., Horan, Timothy, Yano, Naohiro, Kim, KyuKwang, MacLaughlan, Shannon, Lambert-Messerlian, Geralyn, Tseng, YiTang Don, Padbury, James F., Miller, M. Craig, Lange, Thilo S., Singh, Rakesh K.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880958/
https://ncbi.nlm.nih.gov/pubmed/24389815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03574
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