Temporally controlled overexpression of cardiac-specific PI3Kα induces enhanced myocardial contractility—a new transgenic model

The phosphatidylinositol 3-kinase (PI3K) signaling pathway regulates multiple cellular processes including cell survival/apoptosis and growth. In the cardiac context, PI3Kα plays important roles in cardiac growth. We have shown that cardiac PI3K activity is highly regulated during development, with...

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Detalhes bibliográficos
Main Authors: Yano, Naohiro, Tseng, Andy, Zhao, Ting C., Robbins, Jeffrey, Padbury, James F., Tseng, Yi-Tang
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593510/
https://ncbi.nlm.nih.gov/pubmed/18723766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00531.2008
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