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Reversion of a Chinese Hamster Cell Auxotrophic Mutant

A mutant cell strain derived from a Chinese hamster line by mutagenesis with ethylmethane sulfonate requires glycine for growth. In the wild type, glycine synthesis is catalyzed by serine hydroxymethyltransferase (EC 2.1.2.1). Cell fractionation by differential centrifugation and isopycnic sucrose g...

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Détails bibliographiques
Auteurs principaux: Chasin, Lawrence A., Feldman, Aileen, Konstam, Marvin, Urlaub, Gail
Format: Artigo
Langue:Inglês
Publié: 1974
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC388084/
https://ncbi.nlm.nih.gov/pubmed/4362629
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