Transduction-Specific ATLAS (TS-ATLAS) reveals a cohort of highly active L1 retrotransposons in human populations

Long INterspersed Element-1 (LINE-1 or L1) retrotransposons are the only autonomously active transposable elements in the human genome. The average human genome contains ∼80-100 active L1s, but only a subset of these L1s are highly active or ‘hot’. Human L1s are closely related in sequence, making i...

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Main Authors: Macfarlane, Catriona M., Collier, Pamela, Rahbari, Raheleh, Beck, Christine R., Wagstaff, John F., Igoe, Samantha, Moran, John V., Badge, Richard M.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880804/
https://ncbi.nlm.nih.gov/pubmed/23553801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.22327
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