LINE-1 Retrotransposition Activity in Human Genomes

Long Interspersed Element-1 (LINE-1 or L1) sequences comprise the bulk of retrotransposition activity in the human genome; however, the abundance of highly active or ‘hot’ L1s in the human population remains largely unexplored. Here, we used a fosmid-based, paired-end DNA sequencing strategy to iden...

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Bibliographic Details
Main Authors: Beck, Christine R., Collier, Pamela, Macfarlane, Catriona, Malig, Maika, Kidd, Jeffrey M., Eichler, Evan E., Badge, Richard M., Moran, John V.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013285/
https://ncbi.nlm.nih.gov/pubmed/20602998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.05.021
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