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L1 Hybridization Enrichment: A Method for Directly Accessing De Novo L1 Insertions in the Human Germline

Long interspersed nuclear element 1 (L1) retrotransposons are the only autonomously mobile human transposable elements. L1 retrotransposition has shaped our genome via insertional mutagenesis, sequence transduction, pseudogene formation, and ectopic recombination. However, L1 germline retrotransposi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Freeman, Peter, Macfarlane, Catriona, Collier, Pamela, Jeffreys, Alec J, Badge, Richard M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley Subscription Services, Inc., A Wiley Company 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412225/
https://ncbi.nlm.nih.gov/pubmed/21560187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.21533
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