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DNA Enrichment by Allele-Specific Hybridization (DEASH): A Novel Method for Haplotyping and for Detecting Low-Frequency Base Substitutional Variants and Recombinant DNA Molecules
Detecting rare sequence variants in genomic DNA is central to the analysis of de novo mutation and recombination events and the detection of rare pathological mutations in mixed cell populations. Current PCR techniques suffer from noise that limits detection to variants present at a frequency of at...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2003
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC403713/ https://ncbi.nlm.nih.gov/pubmed/14525930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.1214603 |
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