Quantification of Pregenomic RNA and Covalently Closed Circular DNA in Hepatitis B Virus-Related Hepatocellular Carcinoma

Pregenomic RNA (pgRNA) is generated from covalently closed circular DNA (cccDNA) and plays important roles in viral genome amplification and replication. Hepatic pgRNA and cccDNA expression levels indicate viral persistence and replication activity. This study was aimed to measure hepatic pgRNA and...

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Autors principals: Bai, Fugui, Yano, Yoshihiko, Fukumoto, Takumi, Takebe, Atsushi, Tanaka, Motofumi, Kuramitsu, Kaori, Anggorowati, Nungki, Rinonce, Hanggoro Tri, Widasari, Dewiyani Indah, Saito, Masaya, Hirano, Hirotaka, Hayakumo, Takanobu, Seo, Yasushi, Azuma, Takeshi, Ku, Yonson, Hayashi, Yoshitake
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880697/
https://ncbi.nlm.nih.gov/pubmed/24455286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/849290
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