Quantification of Pregenomic RNA and Covalently Closed Circular DNA in Hepatitis B Virus-Related Hepatocellular Carcinoma

Pregenomic RNA (pgRNA) is generated from covalently closed circular DNA (cccDNA) and plays important roles in viral genome amplification and replication. Hepatic pgRNA and cccDNA expression levels indicate viral persistence and replication activity. This study was aimed to measure hepatic pgRNA and...

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Detalhes bibliográficos
Main Authors: Bai, Fugui, Yano, Yoshihiko, Fukumoto, Takumi, Takebe, Atsushi, Tanaka, Motofumi, Kuramitsu, Kaori, Anggorowati, Nungki, Rinonce, Hanggoro Tri, Widasari, Dewiyani Indah, Saito, Masaya, Hirano, Hirotaka, Hayakumo, Takanobu, Seo, Yasushi, Azuma, Takeshi, Ku, Yonson, Hayashi, Yoshitake
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880697/
https://ncbi.nlm.nih.gov/pubmed/24455286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/849290
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