Quantification of Pregenomic RNA and Covalently Closed Circular DNA in Hepatitis B Virus-Related Hepatocellular Carcinoma

Pregenomic RNA (pgRNA) is generated from covalently closed circular DNA (cccDNA) and plays important roles in viral genome amplification and replication. Hepatic pgRNA and cccDNA expression levels indicate viral persistence and replication activity. This study was aimed to measure hepatic pgRNA and...

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Main Authors: Bai, Fugui, Yano, Yoshihiko, Fukumoto, Takumi, Takebe, Atsushi, Tanaka, Motofumi, Kuramitsu, Kaori, Anggorowati, Nungki, Rinonce, Hanggoro Tri, Widasari, Dewiyani Indah, Saito, Masaya, Hirano, Hirotaka, Hayakumo, Takanobu, Seo, Yasushi, Azuma, Takeshi, Ku, Yonson, Hayashi, Yoshitake
格式: Artigo
語言:Inglês
出版: Hindawi Publishing Corporation 2013
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880697/
https://ncbi.nlm.nih.gov/pubmed/24455286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/849290
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