Quantification of Pregenomic RNA and Covalently Closed Circular DNA in Hepatitis B Virus-Related Hepatocellular Carcinoma

Pregenomic RNA (pgRNA) is generated from covalently closed circular DNA (cccDNA) and plays important roles in viral genome amplification and replication. Hepatic pgRNA and cccDNA expression levels indicate viral persistence and replication activity. This study was aimed to measure hepatic pgRNA and...

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Библиографические подробности
Главные авторы: Bai, Fugui, Yano, Yoshihiko, Fukumoto, Takumi, Takebe, Atsushi, Tanaka, Motofumi, Kuramitsu, Kaori, Anggorowati, Nungki, Rinonce, Hanggoro Tri, Widasari, Dewiyani Indah, Saito, Masaya, Hirano, Hirotaka, Hayakumo, Takanobu, Seo, Yasushi, Azuma, Takeshi, Ku, Yonson, Hayashi, Yoshitake
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 2013
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880697/
https://ncbi.nlm.nih.gov/pubmed/24455286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/849290
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