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Using genetic methods to define the targets of compounds with antimalarial activity

Although phenotypic cellular screening has been used to drive antimalarial drug discovery in recent years, in some cases target-based drug discovery remains more attractive. This is especially true when appropriate high-throughput cellular assays are lacking, as is the case for drug discovery effort...

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Bibliografiska uppgifter
Huvudupphovsmän: Flannery, Erika L., Fidock, David A., Winzeler, Elizabeth A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880619/
https://ncbi.nlm.nih.gov/pubmed/23927658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm400325j
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