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The role of reduced intracellular concentrations of active drugs in the lack of response to anticancer chemotherapy
A major difficulty in the treatment of cancers is the poor response of many tumors to pharmacological regimens. This situation can be accounted for by the existence of a variety of complex mechanisms of chemoresistance (MOCs), leading to reduced intracellular concentrations of active agents, changes...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3880477/ https://ncbi.nlm.nih.gov/pubmed/24317012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2013.131 |
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