Tie2 Signaling Cooperates with TNF to Promote the Pro-Inflammatory Activation of Human Macrophages Independently of Macrophage Functional Phenotype

Angiopoietin (Ang) -1 and -2 and their receptor Tie2 play critical roles in regulating angiogenic processes during development, homeostasis, tumorigenesis, inflammation and tissue repair. Tie2 signaling is best characterized in endothelial cells, but a subset of human and murine circulating monocyte...

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Autors principals: García, Samuel, Krausz, Sarah, Ambarus, Carmen A., Fernández, Beatriz Malvar, Hartkamp, Linda M., van Es, Inge E., Hamann, Jörg, Baeten, Dominique L., Tak, Paul P., Reedquist, Kris A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880273/
https://ncbi.nlm.nih.gov/pubmed/24404127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082088
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