Sclerostin Is Positively Associated With Bone Mineral Density in Men and Women and Negatively Associated With Carotid Calcified Atherosclerotic Plaque in Men From the African American-Diabetes Heart Study

CONTEXT: Bone mineral density (BMD) and calcified atherosclerotic plaque (CP) demonstrate inverse relationships. Sclerostin, an endogenous regulator of the Wnt pathway and bone formation, has been associated with impaired osteoblast activation and may play a role in vascular calcification. OBJECTIVE...

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Bibliographic Details
Main Authors: Register, Thomas C., Hruska, Keith A., Divers, Jasmin, Bowden, Donald W., Palmer, Nicholette D., Carr, J. Jeffrey, Wagenknecht, Lynne E., Hightower, R. Caresse, Xu, Jianzhao, Smith, S. Carrie, Dietzen, Dennis J., Langefeld, Carl D., Freedman, Barry I.
Format: Artigo
Language:Inglês
Published: Endocrine Society 2014
Subjects:
Endocrine Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879670/
https://ncbi.nlm.nih.gov/pubmed/24178795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2013-3168
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