Sclerostin Is Positively Associated With Bone Mineral Density in Men and Women and Negatively Associated With Carotid Calcified Atherosclerotic Plaque in Men From the African American-Diabetes Heart Study

CONTEXT: Bone mineral density (BMD) and calcified atherosclerotic plaque (CP) demonstrate inverse relationships. Sclerostin, an endogenous regulator of the Wnt pathway and bone formation, has been associated with impaired osteoblast activation and may play a role in vascular calcification. OBJECTIVE...

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Detalhes bibliográficos
Main Authors: Register, Thomas C., Hruska, Keith A., Divers, Jasmin, Bowden, Donald W., Palmer, Nicholette D., Carr, J. Jeffrey, Wagenknecht, Lynne E., Hightower, R. Caresse, Xu, Jianzhao, Smith, S. Carrie, Dietzen, Dennis J., Langefeld, Carl D., Freedman, Barry I.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2014
Assuntos:
Endocrine Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879670/
https://ncbi.nlm.nih.gov/pubmed/24178795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2013-3168
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