Sclerostin Is Positively Associated With Bone Mineral Density in Men and Women and Negatively Associated With Carotid Calcified Atherosclerotic Plaque in Men From the African American-Diabetes Heart Study

CONTEXT: Bone mineral density (BMD) and calcified atherosclerotic plaque (CP) demonstrate inverse relationships. Sclerostin, an endogenous regulator of the Wnt pathway and bone formation, has been associated with impaired osteoblast activation and may play a role in vascular calcification. OBJECTIVE...

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Main Authors: Register, Thomas C., Hruska, Keith A., Divers, Jasmin, Bowden, Donald W., Palmer, Nicholette D., Carr, J. Jeffrey, Wagenknecht, Lynne E., Hightower, R. Caresse, Xu, Jianzhao, Smith, S. Carrie, Dietzen, Dennis J., Langefeld, Carl D., Freedman, Barry I.
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2014
Fag:
Endocrine Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879670/
https://ncbi.nlm.nih.gov/pubmed/24178795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2013-3168
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