Insulin-Dependent Regulation of Insulin Receptor Concentrations: A Direct Demonstration in Cell Culture
Chronic (5-16 hr) exposure of cultured human lymphocytes to 10(-8) M insulin at 37° in vitro produced a decrease in insulin receptor concentrations unaccounted for by simple occupancy of sites; acute exposure (0-2 hr) was without effect. These results reproduced observations in vivo where chronic hy...
Zapisane w:
| Wydane w: | Proc Natl Acad Sci U S A |
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| Główni autorzy: | , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
1974
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387937/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4359334/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.1.84 |
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