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Mechanism of Inhibition of Eukaryotic Protein Synthesis by Trichothecene Fungal Toxins

The 12,13-epoxytrichothecenes, a group of sesquiterpenoid fungal antibiotics, inhibit protein synthesis in eukaryotic cells but do not share a common mode of action. Trichodermin stabilizes polyribosomes, prevents their disaggregation by puromycin, and also prevents the release of nascent peptides f...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cundliffe, Eric, Cannon, Michael, Davies, Julian
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1974
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC387925/
https://ncbi.nlm.nih.gov/pubmed/4521056
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