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Metabolic QTL Analysis Links Chloroquine Resistance in Plasmodium falciparum to Impaired Hemoglobin Catabolism

Drug resistant strains of the malaria parasite, Plasmodium falciparum, have rendered chloroquine ineffective throughout much of the world. In parts of Africa and Asia, the coordinated shift from chloroquine to other drugs has resulted in the near disappearance of chloroquine-resistant (CQR) parasite...

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Detalhes bibliográficos
Main Authors: Lewis, Ian A., Wacker, Mark, Olszewski, Kellen L., Cobbold, Simon A., Baska, Katelynn S., Tan, Asako, Ferdig, Michael T., Llinás, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879234/
https://ncbi.nlm.nih.gov/pubmed/24391526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004085
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