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Chloroquine Susceptibility and Reversibility in a Plasmodium falciparum Genetic Cross

Mutations in the Plasmodium falciparum chloroquine (CQ) resistance transporter (PfCRT), are major determinants of verapamil (VP)-reversible CQ resistance (CQR). In the presence of mutant PfCRT, additional genes contribute to the wide range of CQ susceptibilities observed. It is not known if these ge...

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Autors principals: Patel, Jigar J., Thacker, Drew, Tan, John C., Pleeter, Perri, Checkley, Lisa, Gonzales, Joseph M., Deng, Bingbing, Roepe, Paul D., Cooper, Roland A., Ferdig, Michael T.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091165/
https://ncbi.nlm.nih.gov/pubmed/20807203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2010.07366.x
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