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PLASMODIUM FALCIPARUM Na(+)/H(+) EXCHANGER ACTIVITY AND QUININE RESISTANCE
Mutations in the Plasmodium falciparum pfcrt gene cause resistance to the 4 – amino quinoline chloroquine (CQ) and other antimalarial drugs. Mutations and/or overexpression of a P. falciparum multidrug resistance gene homologue (pfmdr1) may further modify or tailor the degree of quinoline drug resis...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2747254/ https://ncbi.nlm.nih.gov/pubmed/17353059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2007.01.018 |
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