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Loss of PINK1 enhances neurodegeneration in a mouse model of Parkinson's disease triggered by mitochondrial stress()

Parkinson's disease (PD) shows a complex etiology, where both genetic and environmental factors contribute to initiation and advance of pathology. Mitochondrial dysfunction and mutation of genes implicated in mitochondria quality control are recognized contributors to etiopathology and progress...

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Detalhes bibliográficos
Main Authors: Moisoi, Nicoleta, Fedele, Valentina, Edwards, Jennifer, Martins, L. Miguel
Formato: Artigo
Idioma:Inglês
Publicado em: Pergamon Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878764/
https://ncbi.nlm.nih.gov/pubmed/24161480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2013.10.009
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