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The Extra Cytoplasmic Function Sigma Factor σ(E) Is Essential for Mycobacterium tuberculosis Virulence in Mice
The virulence of a Mycobacterium tuberculosis H37Rv sigE mutant was studied in immunodeficient and immunocompetent mice. The mutant was strongly attenuated in both animal models and induced formation of granulomas with different characteristics than those induced by the wild-type strain.
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology
2004
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC387853/ https://ncbi.nlm.nih.gov/pubmed/15102817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.5.3038-3041.2004 |
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