Posttranslational Regulation of Mycobacterium tuberculosis Extracytoplasmic-Function Sigma Factor σ(L) and Roles in Virulence and in Global Regulation of Gene Expression

In this report, we demonstrate that SigL is posttranslationally regulated by a specific anti-sigma factor, RslA, and contributes to the expression of at least 28 genes. Several of these genes could mediate important cell envelope-related processes. Importantly, a sigL-rslA mutant strain was signific...

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Bibliographische Detailangaben
Hauptverfasser: Dainese, Elisa, Rodrigue, Sébastien, Delogu, Giovanni, Provvedi, Roberta, Laflamme, Liette, Brzezinski, Ryszard, Fadda, Giovanni, Smith, Issar, Gaudreau, Luc, Palù, Giorgio, Manganelli, Riccardo
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
Schlagworte:
Molecular Pathogenesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1418919/
https://ncbi.nlm.nih.gov/pubmed/16552079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.4.2457-2461.2006
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