Activation of cellular immunity and marked inhibition of liver cancer in a mouse model following gene therapy and tumor expression of GM-SCF, IL-21, and Rae-1

BACKGROUND: Cancer is both a systemic and a genetic disease. The pathogenesis of cancer might be related to dampened immunity. Host immunity recognizes nascent malignant cells – a process referred to as immune surveillance. Augmenting immune surveillance and suppressing immune escape are crucial in...

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Detalhes bibliográficos
Main Authors: Cheng, Mingrong, Zhi, Kangkang, Gao, Xiaoyan, He, Bing, Li, Yingchun, Han, Jiang, Zhang, Zhiping, Wu, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878360/
https://ncbi.nlm.nih.gov/pubmed/24350772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-166
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