Synthesis of liver-targeting dual-ligand modified GCGA/5-FU nanoparticles and their characteristics in vitro and in vivo

Nanoparticle drug delivery systems using polymers hold promise for clinical applications. We synthesized dual-ligand modified chitosan (GCGA) nanoparticles using lactic acid, glycyrrhetinic acid, and chitosan to target the liver in our previous studies. We then synthesized the GCGA/5-FU nanoparticle...

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Detalhes bibliográficos
Main Authors: Cheng, Mingrong, Gao, Xiaoyan, Wang, Yong, Chen, Houxiang, He, Bing, Li, Yingchun, Han, Jiang, Zhang, Zhiping
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826867/
https://ncbi.nlm.nih.gov/pubmed/24232303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S52877
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