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Targeting the PDGF signaling pathway in tumor treatment

Platelet-derived growth factor (PDGF) isoforms and PDGF receptors have important functions in the regulation of growth and survival of certain cell types during embryonal development and e.g. tissue repair in the adult. Overactivity of PDGF receptor signaling, by overexpression or mutational events,...

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Detalhes bibliográficos
Autor principal: Heldin, Carl-Henrik
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878225/
https://ncbi.nlm.nih.gov/pubmed/24359404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-11-97
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