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Targeting the PDGF signaling pathway in tumor treatment

Platelet-derived growth factor (PDGF) isoforms and PDGF receptors have important functions in the regulation of growth and survival of certain cell types during embryonal development and e.g. tissue repair in the adult. Overactivity of PDGF receptor signaling, by overexpression or mutational events,...

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Hlavní autor: Heldin, Carl-Henrik
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878225/
https://ncbi.nlm.nih.gov/pubmed/24359404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-11-97
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