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Dominant-Negative Myosin Va Impairs Retrograde but Not Anterograde Axonal Transport of Large Dense Core Vesicles

Axonal transport of peptide and hormone-containing large dense core vesicles (LDCVs) is known to be a microtubule-dependent process. Here, we suggest a role for the actin-based motor protein myosin Va specifically in retrograde axonal transport of LDCVs. Using live-cell imaging of transfected hippoc...

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Detalhes bibliográficos
Main Authors: Bittins, Claudia Margarethe, Eichler, Tilo Wolf, Hammer, John A., Gerdes, Hans-Hermann
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878150/
https://ncbi.nlm.nih.gov/pubmed/19787448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10571-009-9459-2
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