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Identification of an Axonal Kinesin-3 Motor for Fast Anterograde Vesicle Transport that Facilitates Retrograde Transport of Neuropeptides

A screen for genes required in Drosophila eye development identified an UNC-104/Kif1 related kinesin-3 microtubule motor. Analysis of mutants suggested that Drosophila Unc-104 has neuronal functions that are distinct from those of the classic anterograde axonal motor, kinesin-1. In particular, unc-1...

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Autors principals: Barkus, Rosemarie V., Klyachko, Olga, Horiuchi, Dai, Dickson, Barry J., Saxton, William M.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174192/
https://ncbi.nlm.nih.gov/pubmed/17989365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-03-0261
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