Llwytho...

Dynamic interplay of oncogenes and T cells impacts induction of PD-1 expression in the tumor microenvironment

Tumor infiltrating T cells have recently been found to upregulate immunosuppressive pathways, such as PD-1 ligand (PD-L1), in a paracrine fashion on tumor cells, but tumor cell intrinsic regulation of PD-L1 is another potential mechanism. In this issue of Cancer Discovery, Akbay and colleagues show...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rech, Andrew J., Vonderheide, Robert H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877936/
https://ncbi.nlm.nih.gov/pubmed/24327693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-13-0775
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