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Regulation of PD-L1 expression in the tumor microenvironment

Programmed death-ligand 1 (PD-L1) on cancer cells engages with programmed cell death-1 (PD-1) on immune cells, contributing to cancer immune escape. For multiple cancer types, the PD-1/PD-L1 axis is the major speed-limiting step of the anti-cancer immune response. In this context, blocking PD-1/PD-L...

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Bibliografiske detaljer
Udgivet i:J Hematol Oncol
Main Authors: Yi, Ming, Niu, Mengke, Xu, Linping, Luo, Suxia, Wu, Kongming
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7792099/
https://ncbi.nlm.nih.gov/pubmed/33413496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-020-01027-5
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