Learning improvement after PI3K activation correlates with de novo formation of functional small spines

PI3K activation promotes the formation of synaptic contacts and dendritic spines, morphological features of glutamatergic synapses that are commonly known to be related to learning processes. In this report, we show that in vivo administration of a peptide that activates the PI3K signaling pathway i...

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Bibliografski detalji
Glavni autori: Enriquez-Barreto, Lilian, Cuesto, Germán, Dominguez-Iturza, Nuria, Gavilán, Elena, Ruano, Diego, Sandi, Carmen, Fernández-Ruiz, Antonio, Martín-Vázquez, Gonzalo, Herreras, Oscar, Morales, Miguel
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2014
Teme:
Neuroscience
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877779/
https://ncbi.nlm.nih.gov/pubmed/24427113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2013.00054
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