Learning improvement after PI3K activation correlates with de novo formation of functional small spines

PI3K activation promotes the formation of synaptic contacts and dendritic spines, morphological features of glutamatergic synapses that are commonly known to be related to learning processes. In this report, we show that in vivo administration of a peptide that activates the PI3K signaling pathway i...

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Detalhes bibliográficos
Main Authors: Enriquez-Barreto, Lilian, Cuesto, Germán, Dominguez-Iturza, Nuria, Gavilán, Elena, Ruano, Diego, Sandi, Carmen, Fernández-Ruiz, Antonio, Martín-Vázquez, Gonzalo, Herreras, Oscar, Morales, Miguel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877779/
https://ncbi.nlm.nih.gov/pubmed/24427113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2013.00054
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