Targeted Disruption of the Ribosomal Protein S19 Gene Is Lethal Prior to Implantation

The ribosomal protein S19 (RPS19) is located in the small (40S) subunit and is one of 79 ribosomal proteins. The gene encoding RPS19 is mutated in approximately 25% of patients with Diamond-Blackfan anemia, which is a rare congenital erythroblastopenia. Affected individuals present with decreased nu...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Matsson, Hans, Davey, Edward J., Draptchinskaia, Natalia, Hamaguchi, Isao, Ooka, Andreas, Levéen, Per, Forsberg, Erik, Karlsson, Stefan, Dahl, Niklas
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 2004
Schlagworte:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387766/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15082795/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.9.4032-4037.2004
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