In Vitro Processing of the 3′-Overhanging DNA in the Postcleavage Complex Involved in V(D)J Joining

The postcleavage complex involved in V(D)J joining is known to possess a transpositional strand transfer activity, whose physiological role is yet to be clarified. Here we report that RAG1 and RAG2 proteins in the signal end (SE) complex cleave the 3′-overhanging structure of the synthetic coding-en...

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Autors principals: Nishihara, Tadashi, Nagawa, Fumikiyo, Nishizumi, Hirofumi, Kodama, Masami, Hirose, Satoshi, Hayashi, Reiko, Sakano, Hitoshi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
DNA Dynamics and Chromosome Structure
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC387758/
https://ncbi.nlm.nih.gov/pubmed/15082765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.9.3692-3702.2004
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