MicroRNA-494 Within an Oncogenic MicroRNA Megacluster Regulates G(1)/S Transition in Liver Tumorigenesis Through Suppression of Mutated in Colorectal Cancer

Hepatocellular carcinoma (HCC) is associated with poor survival for patients and few effective treatment options, raising the need for novel therapeutic strategies. MicroRNAs (miRNAs) play important roles in tumor development and show deregulated patterns of expression in HCC. Because of the liver’s...

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Detalhes bibliográficos
Main Authors: Lim, Lionel, Balakrishnan, Asha, Huskey, Noelle, Jones, Kirk D, Jodari, Mona, Ng, Raymond, Song, Guisheng, Riordan, Jesse, Anderton, Brittany, Cheung, Siu-Tim, Willenbring, Holger, Dupuy, Adam, Chen, Xin, Brown, David, Chang, Aaron N, Goga, Andrei
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Hepatobiliary Malignancies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877416/
https://ncbi.nlm.nih.gov/pubmed/23913442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26662
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