MicroRNA-494 is a master epigenetic regulator of multiple invasion-suppressor microRNAs by targeting ten eleven translocation 1 in invasive human hepatocellular carcinoma tumors

Vascular invasion provides a direct route for tumor metastasis. The degree to which microRNA (miRNA) expression plays a role in tumor vascular invasion is unclear. Here, we report that miR-494 is up-regulated in human hepatocellular carcinoma (HCC) tumors with vascular invasion and can promote HCC c...

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Bibliographic Details
Published in:Hepatology
Main Authors: Chuang, Kuang-Hsiang, Whitney-Miller, Christa L, Chu, Chin-Yi, Zhou, Zhongren, Dokus, M Katherine, Schmit, Shannon, Barry, Christopher T
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Ltd 2015
Subjects:
Hepatobiliary Malignancies
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682466/
https://ncbi.nlm.nih.gov/pubmed/25820676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27816
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