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Quantifying Intrinsic and Extrinsic Variability in Stochastic Gene Expression Models

Genetically identical cell populations exhibit considerable intercellular variation in the level of a given protein or mRNA. Both intrinsic and extrinsic sources of noise drive this variability in gene expression. More specifically, extrinsic noise is the expression variability that arises from cell...

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Bibliographic Details
Main Authors: Singh, Abhyudai, Soltani, Mohammad
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877255/
https://ncbi.nlm.nih.gov/pubmed/24391934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084301
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