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Transcriptional Bursting in Gene Expression: Analytical Results for General Stochastic Models

Gene expression in individual cells is highly variable and sporadic, often resulting in the synthesis of mRNAs and proteins in bursts. Such bursting has important consequences for cell-fate decisions in diverse processes ranging from HIV-1 viral infections to stem-cell differentiation. It is general...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Kumar, Niraj, Singh, Abhyudai, Kulkarni, Rahul V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608583/
https://ncbi.nlm.nih.gov/pubmed/26474290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004292
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