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Transcriptional Bursting in Gene Expression: Analytical Results for General Stochastic Models

Gene expression in individual cells is highly variable and sporadic, often resulting in the synthesis of mRNAs and proteins in bursts. Such bursting has important consequences for cell-fate decisions in diverse processes ranging from HIV-1 viral infections to stem-cell differentiation. It is general...

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Udgivet i:PLoS Comput Biol
Main Authors: Kumar, Niraj, Singh, Abhyudai, Kulkarni, Rahul V.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608583/
https://ncbi.nlm.nih.gov/pubmed/26474290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004292
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