Effects of Age on Bone mRNA Levels of Sclerostin and Other Genes Relevant to Bone Metabolism in Humans

Although aging is associated with a decline in bone formation in humans, the molecular pathways contributing to this decline remain unclear. Several previous clinical studies have shown that circulating sclerostin levels increase with age, raising the possibility that increased production of scleros...

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Main Authors: Roforth, Matthew M., Fujita, Koji, McGregor, Ulrike I., Kirmani, Salman, McCready, Louise K., Peterson, James M., Drake, Matthew T., Monroe, David G., Khosla, Sundeep
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877168/
https://ncbi.nlm.nih.gov/pubmed/24184314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2013.10.019
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