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Hormonal and Systemic Regulation of Sclerostin
The Wnt/β-catenin signaling pathway plays an essential role in osteoblast biology. Sclerostin is a soluble antagonist of Wnt/β-catenin signaling secreted primarily by osteocytes. Current evidence indicates that sclerostin likely functions as a local/paracrine regulator of bone metabolism rather than...
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| Publicado no: | Bone |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5329134/ https://ncbi.nlm.nih.gov/pubmed/27965160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2016.12.004 |
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