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Effects of Parathyroid Hormone Treatment on Circulating Sclerostin Levels in Postmenopausal Women

Context: Intermittent PTH treatment stimulates bone formation, but the mechanism(s) of this effect remain unclear. Sclerostin is an inhibitor of Wnt signaling, and animal studies have demonstrated that PTH suppresses sclerostin production. Objective: The objective of the study was to test whether in...

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Detalhes bibliográficos
Main Authors: Drake, Matthew T., Srinivasan, Bhuma, Mödder, Ulrike I., Peterson, James M., McCready, Louise K., Riggs, B. Lawrence, Dwyer, Denise, Stolina, Marina, Kostenuik, Paul, Khosla, Sundeep
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2968729/
https://ncbi.nlm.nih.gov/pubmed/20631014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2010-0720
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