A Screen for Genetic Suppressor Elements of Hepatitis C Virus Identifies a Supercharged Protein Inhibitor of Viral Replication

Genetic suppressor elements (GSEs) are biomolecules derived from a gene or genome of interest that act as transdominant inhibitors of biological functions presumably by disruption of critical biological interfaces. We exploited a cell death reporter cell line for hepatitis C virus (HCV) infection, n...

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Bibliographic Details
Main Authors: Simeon, Rudo L., Chen, Zhilei
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877138/
https://ncbi.nlm.nih.gov/pubmed/24391867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084022
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