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Genetic Analysis of Serum-Derived Defective Hepatitis C Virus Genomes Revealed Novel Viral cis Elements for Virus Replication and Assembly

Defective viral genomes (DVGs) of hepatitis C virus (HCV) exist, but their biological significances have not been thoroughly investigated. Here, we analyzed HCV DVGs circulating in patient sera that possess deletions in the structural protein-encoding region. About 30% of 41 HCV clinical isolates po...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Li, Qingchao, Tong, Yimin, Xu, Yongfen, Niu, Junqi, Zhong, Jin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972877/
https://ncbi.nlm.nih.gov/pubmed/29367245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02182-17
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