Loss of Multi-Epitope Specificity in Memory CD4(+) T Cell Responses to B. Pertussis with Age

Pertussis is still occurring in highly vaccinated populations, affecting individuals of all ages. Long-lived Th1 CD4(+) T cells are essential for protective immunity against pertussis. For better understanding of the limited immunological memory to Bordetella pertussis, we used a panel of Pertactin...

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書誌詳細
主要な著者: Han, Wanda G. H., van Twillert, Inonge, Poelen, Martien C. M., Helm, Kina, van de Kassteele, Jan, Verheij, Theo J. M., Versteegh, Florens G. A., Boog, Claire J. P., van Els, Cécile A. C. M.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877060/
https://ncbi.nlm.nih.gov/pubmed/24391789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083583
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