Intravesical Toll-like receptor 7 agonist R-837: Optimization of its formulation in an orthotopic mouse model of bladder cancer

OBJECTIVE: To study the immune response caused by the intravesical administration of the immunomodulator R-837 in various formulations and to estimate its therapeutic potential for bladder cancer. METHODS: Female C57BL/6 mice were intravesically treated with different formulations of R-837, a Toll-l...

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Bibliographic Details
Main Authors: Hayashi, Tomoko, Crain, Brian, Corr, Maripat, Chan, Michael, Cottam, Howard B, Maj, Roberto, Barberis, Alcide, Leoni, Lorenzo, Carson, Dennis A
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876967/
https://ncbi.nlm.nih.gov/pubmed/20337728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1442-2042.2010.02503.x
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